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COL8A1 Antibody

CAT: 0223-59-065Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-59-065Size:400 µL
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Background
This gene encodes one of the two alpha chains of type VIII collagen. The gene product is a short chain collagen and a major component of the basement membrane of the corneal endothelium. The type VIII collagen fibril can be either a homo- or a heterotrimer. Alternatively spliced transcript variants encoding the same isoform have been observed.
NCBI Gene ID
1295
Swiss Prot
P27658
Accession Number
P27658
Host
Rabbit
Reactivity
Human
Immunogen
This COL8A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 62-89 amino acids from the N-terminal region of human COL8A1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
73 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
COL8A1
NCBI Official Name
Collagen alpha-1 (VIII) chain
NCBI Organism
Homo sapiens
Background Reference 01
Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)
Background Reference 02
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background Reference 03
Neale, B.M., et al. Proc. Natl. Acad. Sci. U.S.A. 107 (16) :7395-7400 (2010)
Background Reference 04
Talmud, P.J., et al. Am. J. Hum. Genet. 85 (5) :628-642 (2009)
Other Product Names
Collagen alpha-1 (VIII) chain, Endothelial collagen, Vastatin, COL8A1, C3orf7
Tested Applications
WB
Protein ID
21903375
Physical Properties
Liquid

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