COL8A1 Antibody

• Background:

  This gene encodes one of the two alpha chains of type VIII collagen. The gene product is a short chain collagen and a major component of the basement membrane of the corneal endothelium. The type VIII collagen fibril can be either a homo- or a heterotrimer. Alternatively spliced transcript variants encoding the same isoform have been observed.

• NCBI Gene ID:

  1295

• Swiss Prot:

  P27658

• Accession Number:

  P27658

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This COL8A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 62-89 amino acids from the N-terminal region of human COL8A1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  73 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  COL8A1

• NCBI Official Name:

  Collagen alpha-1 (VIII) chain

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)

• Background Reference 02:

  Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :

• Background Reference 03:

  Neale, B.M., et al. Proc. Natl. Acad. Sci. U.S.A. 107 (16) :7395-7400 (2010)

• Background Reference 04:

  Talmud, P.J., et al. Am. J. Hum. Genet. 85 (5) :628-642 (2009)

• Other Product Names:

  Collagen alpha-1 (VIII) chain, Endothelial collagen, Vastatin, COL8A1, C3orf7

• Tested Applications:

  WB

• Protein ID:

  21903375

• Physical Properties:

  Liquid