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COL3A1 Antibody

CAT: 0223-57-533Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-57-533Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes the pro-alpha1 chains of type III collagen, a fibrillar collagen that is found in extensible connective tissues such as skin, lung, uterus, intestine and the vascular system, frequently in association with type I collagen. Mutations in this gene are associated with Ehlers-Danlos syndrome types IV, and with aortic and arterial aneurysms. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene. [provided by R. Dalgleish].
NCBI Gene ID
1281
Swiss Prot
P02461
Accession Number
P02461
Host
Rabbit
Reactivity
Human
Immunogen
This COL3A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1410-1438 amino acids from the C-terminal region of human COL3A1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
139 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
COL3A1
NCBI Official Name
Collagen alpha-1 (III) chain
NCBI Organism
Homo sapiens
Background Reference 01
Romero, R., et al. Am. J. Obstet. Gynecol. 203 (4), 361 (2010) :
Background Reference 02
Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)
Background Reference 03
Romero, R., et al. Am. J. Obstet. Gynecol. 202 (5), 431 (2010) :
Background Reference 04
Taddese, S., et al. Biochim. Biophys. Acta 1804 (4) :731-739 (2010)
Other Product Names
Collagen alpha-1 (III) chain, COL3A1
Tested Applications
WB
Protein ID
124056490
Physical Properties
Liquid

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