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PRKAR1B Antibody

CAT: 0223-59-017Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-59-017Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Cyclic AMP-dependent protein kinase A (PKA) is an essential enzyme in the signaling pathway of the second messenger cAMP. Through phosphorylation of target proteins, PKA controls many biochemical events in the cell including regulation of metabolism, ion transport, and gene transcription. The PKA holoenzyme is composed of 2 regulatory and 2 catalytic subunits and dissociates from the regulatory subunits upon binding of cAMP.[supplied by OMIM].
NCBI Gene ID
5575
Swiss Prot
P31321
Accession Number
P31321
Host
Rabbit
Reactivity
Human
Immunogen
This PRKAR1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 55-84 amino acids from the N-terminal region of human PRKAR1B.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Obesity, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
43 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
PRKAR1B
NCBI Official Name
CAMP-dependent protein kinase type I-beta regulatory subunit
NCBI Organism
Homo sapiens
Background Reference 01
Silva, L.K., et al. Eur. J. Hum. Genet. (2010) In press :
Background Reference 02
Liu, Y.J., et al. Obesity (Silver Spring) (2010) In press :
Background Reference 03
Zhan, X., et al. Anal. Biochem. 354 (2) :279-289 (2006)
Background Reference 04
Gullingsrud, J., et al. Structure 14 (1) :141-149 (2006)
Other Product Names
CAMP-dependent protein kinase type I-beta regulatory subunit, PRKAR1B
Tested Applications
WB
Protein ID
229463042
Physical Properties
Liquid

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