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PRKAG1 Antibody

CAT: 0223-22-846Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-22-846Size:100 µL
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Background
The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK) . AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
NCBI Gene ID
5571
Swiss Prot
P54619
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-331 of human PRKAG1 (NP_002724.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Autophagy, Cancer, Cell Cycle, Signal Transduction
Purification
Affinity purification
Positive Control
Jurkat
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 36kDa/38kDa
Fragment
IgG
Symbol
PRKAG1
Positive Control 2
22Rv1
Positive Control 3
Mouse kidney
Positive Control 4
Mouse thymus
NCBI Official Name
5'-AMP-activated protein kinase subunit gamma-1
NCBI Organism
Homo sapiens
Other Product Names
5'-AMP-activated protein kinase subunit gamma-1, AMPK gamma1, AMPK subunit gamma-1, AMPKg, PRKAG1
Tested Applications
WB, IHC, IF
Physical Properties
Liquid

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