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PRKAA1 Antibody

CAT: 0223-62-773Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-62-773Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
PRKAA1 is a protein belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase. PRKAA1 is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of PRKAA1 is activated by the stimuli that increase the cellular AMP/ATP ratio. PRKAA1 regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways.
NCBI Gene ID
5562
Swiss Prot
Q13131
Accession Number
Q13131
Host
Rabbit
Reactivity
Human
Immunogen
This PRKAA1 antibody is generated from rabbits immunized with a recombinant protein from human PRKAA1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Obesity, Neuroscience, Signal Transduction, Autophagy
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
64 kDa
Fragment
Rabbit Ig
Symbol
PRKAA1
NCBI Official Name
5'-AMP-activated protein kinase catalytic subunit alpha-1
NCBI Organism
Homo sapiens
Background Reference 01
Puissant, A., et.al., Cancer Res. 70 (3), 1042-1052 (2010)
Background Reference 02
McGeachie, M., et.al., Circulation 120 (24), 2448-2454 (2009)
Other Product Names
5'-AMP-activated protein kinase catalytic subunit alpha-1, AMPK subunit alpha-1, Acetyl-CoA carboxylase kinase, ACACA kinase, Hydroxymethylglutaryl-CoA reductase kinase, HMGCR kinase, Tau-protein kinase PRKAA1, PRKAA1, AMPK1
Tested Applications
WB, IHC-P, Flow
Protein ID
254763436
Physical Properties
Liquid

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