PKD2L1 Antibody

• Background:

  PKD2L1 is a member of the polycystin protein family. The encoded protein contains multiple transmembrane domains, and cytoplasmic N- and C-termini. The protein may be an integral membrane protein involved in cell-cell/matrix interactions. This protein functions as a calcium-regulated nonselective cation channel. Alternative splice variants have been described but their full length sequences have not been determined.

• NCBI Gene ID:

  9033

• Swiss Prot:

  Q9P0L9

• Accession Number:

  Q9P0L9

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This PKD2L1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 37-65 amino acids from the N-terminal region of human PKD2L1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  92 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  PKD2L1

• NCBI Official Name:

  Polycystic kidney disease 2-like 1 protein

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Molland, K.L., et al. Biochem. J. 429 (1) :171-183 (2010)

• Background Reference 02:

  Kawaguchi, H., et al. J. Biol. Chem. 285 (23) :17277-17281 (2010)

• Background Reference 03:

  Li, Q., et al. J. Neurochem. 103 (6) :2391-2400 (2007)

• Background Reference 04:

  Geng, L., et al. J. Cell. Sci. 119 (PT 7), 1383-1395 (2006) :

• Other Product Names:

  Polycystic kidney disease 2-like 1 protein, Polycystin-2 homolog, Polycystin-2L1, Polycystin-L, Polycystin-L1, PKD2L1, PKD2L, PKDL, TRPP3

• Tested Applications:

  WB

• Protein ID:

  23821938

• Physical Properties:

  Liquid