PKD2 Antibody

• Background :

  This gene encodes a member of the polycystin protein family. The encoded protein is a multi-pass membrane protein that functions as a calcium permeable cation channel, and is involved in calcium transport and calcium signaling in renal epithelial cells. This protein interacts with polycystin 1, and they may be partners in a common signaling cascade involved in tubular morphogenesis. Mutations in this gene are associated with autosomal dominant polycystic kidney disease type 2.

• NCBI Gene ID :

  5311

• Swiss Prot :

  Q13563

• Host :

  Rabbit

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Recombinant fusion protein containing a sequence corresponding to amino acids 240-410 of human PKD2 (NP_000288.1) .

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Cancer, Cell Cycle, Growth Factors, Neuroscience, Signal Transduction

• Purification :

  Affinity purification

• Positive Control :

  293T

• Concentration :

  Batch dependent

• Buffer :

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  Observed: 110kDa

• Fragment :

  IgG

• Applications Notes :

  WB: 1:500 - 1:1000

• Symbol :

  PKD2

• Positive Control 2 :

  MCF7

• Positive Control 3 :

  Mouse kidney

• NCBI Official Name :

  Polycystic kidney disease 2 (autosomal dominant)

• NCBI Organism :

  Homo sapiens

• Other Product Names :

  Polycystwin, polycystin 2, PKD4, PC2, MGC138468, MGC138466, APKD2, polycystic kidney disease 2 (autosomal dominant), PKD2, Pc-2, TRPP2

• Tested Applications :

  WB

• Physical Properties :

  Liquid