PKD2 Antibody

• Background:

  This gene encodes a member of the polycystin protein family. The encoded protein is a multi-pass membrane protein that functions as a calcium permeable cation channel, and is involved in calcium transport and calcium signaling in renal epithelial cells. This protein interacts with polycystin 1, and they may be partners in a common signaling cascade involved in tubular morphogenesis. Mutations in this gene are associated with autosomal dominant polycystic kidney disease type 2.

• NCBI Gene ID:

  5311

• Swiss Prot:

  Q13563

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 240-410 of human PKD2 (NP_000288.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Cell Cycle, Growth Factors, Neuroscience, Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  293T

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 110kDa

• Fragment:

  IgG

• Applications Notes:

  WB: 1:500 - 1:1000

• Symbol:

  PKD2

• Positive Control 2:

  MCF7

• Positive Control 3:

  Mouse kidney

• NCBI Official Name:

  Polycystic kidney disease 2 (autosomal dominant)

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Polycystwin, polycystin 2, PKD4, PC2, MGC138468, MGC138466, APKD2, polycystic kidney disease 2 (autosomal dominant), PKD2, Pc-2, TRPP2

• Tested Applications:

  WB

• Physical Properties:

  Liquid