COL6A2 Antibody

• Background:

  COL6A2 is one of the three alpha chains of type VI collagen, a beaded filament collagen found in most connective tissues. The product of this gene contains several domains similar to von Willebrand Factor type A domains. These domains have been shown to bind extracellular matrix proteins, an interaction that explains the importance of this collagen in organizing matrix components. Mutations in this gene are associated with Bethlem myopathy and Ullrich scleroatonic muscular dystrophy. Three transcript variants have been identified for this gene. [provided by RefSeq].

• NCBI Gene ID:

  1292

• Swiss Prot:

  P12110

• Accession Number:

  P12110

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This COL6A2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 719-747 amino acids from the C-terminal region of human COL6A2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Mouse

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  109 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  COL6A2

• NCBI Official Name:

  Collagen alpha-2 (VI) chain

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Zhang, R.Z., et al. J. Biol. Chem. 285 (13) :10005-10015 (2010)

• Background Reference 02:

  Bovolenta, M., et al. BMC Med. Genet. 11, 44 (2010) :

• Background Reference 03:

  Chapuis, J., et al. Mol. Psychiatry 14 (11) :1004-1016 (2009)

• Background Reference 04:

  Freise, C., et al. Matrix Biol. 28 (8) :480-489 (2009)

• Other Product Names:

  Collagen alpha-2 (VI) chain, COL6A2

• Tested Applications:

  WB

• Protein ID:

  125987812

• Physical Properties:

  Liquid