COL4A2 Antibody

• Background:

  This gene encodes one of the six subunits of type IV collagen, the major structural component of basement membranes. The C-terminal portion of the protein, known as canstatin, is an inhibitor of angiogenesis and tumor growth. Like the other members of the type IV collagen gene family, this gene is organized in a head-to-head conformation with another type IV collagen gene so that each gene pair shares a common promoter.

• NCBI Gene ID:

  1284

• Swiss Prot:

  P08572

• Accession Number:

  P08572

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This COL4A2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 156-186 amino acids from the N-terminal region of human COL4A2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  168 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  COL4A2

• NCBI Official Name:

  Collagen alpha-2 (IV) chain

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Bianchini, G., et al. J. Clin. Oncol. 28 (28) :4316-4323 (2010)

• Background Reference 02:

  Romero, R., et al. Am. J. Obstet. Gynecol. 203 (4), 361 (2010) :

• Background Reference 03:

  Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)

• Background Reference 04:

  Romero, R., et al. Am. J. Obstet. Gynecol. 202 (5), 431 (2010) :

• Other Product Names:

  Collagen alpha-2 (IV) chain, Canstatin, COL4A2

• Tested Applications:

  WB, Flow

• Protein ID:

  143811377

• Physical Properties:

  Liquid