COL4A2 Antibody

CAT: 0223-55-856Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-55-856Size:400 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes one of the six subunits of type IV collagen, the major structural component of basement membranes. The C-terminal portion of the protein, known as canstatin, is an inhibitor of angiogenesis and tumor growth. Like the other members of the type IV collagen gene family, this gene is organized in a head-to-head conformation with another type IV collagen gene so that each gene pair shares a common promoter.
NCBI Gene ID
1284
Swiss Prot
P08572
Accession Number
P08572
Host
Rabbit
Reactivity
Human
Immunogen
This COL4A2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 156-186 amino acids from the N-terminal region of human COL4A2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
168 kDa
Fragment
Rabbit Ig
Symbol
COL4A2
NCBI Official Name
Collagen alpha-2 (IV) chain
NCBI Organism
Homo sapiens
Background Reference 01
Bianchini, G., et al. J. Clin. Oncol. 28 (28) :4316-4323 (2010)
Background Reference 02
Romero, R., et al. Am. J. Obstet. Gynecol. 203 (4), 361 (2010) :
Background Reference 03
Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)
Background Reference 04
Romero, R., et al. Am. J. Obstet. Gynecol. 202 (5), 431 (2010) :
Other Product Names
Collagen alpha-2 (IV) chain, Canstatin, COL4A2
Tested Applications
WB, Flow
Protein ID
143811377
Physical Properties
Liquid

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