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Mouse Hck Antibody

CAT: 0223-58-266Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-58-266Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is a member of the Src family of tyrosine kinases. This protein is primarily hemopoietic, particularly in cells of the myeloid and B-lymphoid lineages. It may play a role in the innate immune response and the STAT5 signaling pathway. Alternative translation initiation site usage, including a non-AUG (CUG) codon, results in the production of two different isoforms, that have different subcellular localization.
NCBI Gene ID
15162
Swiss Prot
P08103
Accession Number
P08103
Host
Rabbit
Reactivity
Human
Immunogen
This Mouse Hck antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 72-101 amino acids from the N-terminal region of mouse Hck.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
59 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
Hck
NCBI Official Name
Tyrosine-protein kinase HCK
NCBI Organism
Mus musculus
Background Reference 01
Verollet, C., et al. J. Immunol. 184 (12) :7030-7039 (2010)
Background Reference 02
Ruschmann, J., et al. Exp. Hematol. 38 (5) :392-402 (2010)
Background Reference 03
Lowell, C.A., et al. J. Cell Biol. 133 (4) :895-910 (1996)
Background Reference 04
Lowell, C.A., et al. Blood 87 (5) :1780-1792 (1996)
Other Product Names
Tyrosine-protein kinase HCK, B-cell/myeloid kinase, BMK, Hematopoietic cell kinase, Hemopoietic cell kinase, p56-HCK/p59-HCK, Hck
Tested Applications
WB
Physical Properties
Liquid

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