Products for Research Use Only

HCK Antibody

CAT: 0223-63-162Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-63-162Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
HCK is a member of the Src family of tyrosine kinases. This protein is primarily hemopoietic, particularly in cells of the myeloid and B-lymphoid lineages. It may help couple the Fc receptor to the activation of the respiratory burst. In addition, it may play a role in neutrophil migration and in the degranulation of neutrophils. Multiple isoforms with different subcellular distributions are produced due to both alternative splicing and the use of alternative translation initiation codons, including a non-AUG (CUG) codon. [provided by RefSeq].
NCBI Gene ID
3055
Swiss Prot
P08631
Accession Number
P08631
Host
Rabbit
Reactivity
Human
Immunogen
This HCK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 131-156 amino acids from the N-terminal region of human HCK.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse, Rat, Monkey
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
60 kDa
Fragment
Rabbit Ig
Symbol
HCK
NCBI Official Name
Tyrosine-protein kinase HCK
NCBI Organism
Homo sapiens
Background Reference 01
Hassan, R., et al. J. Cell. Physiol. 221 (2) :458-468 (2009)
Background Reference 02
Kennah, E., et al. Blood 113 (19) :4646-4655 (2009)
Background Reference 03
Voss, M., et al. BMC Immunol. 10, 53 (2009) :
Background Reference 04
Rikova, K., et al. Cell 131 (6) :1190-1203 (2007)
Other Product Names
Tyrosine-protein kinase HCK, Hematopoietic cell kinase, Hemopoietic cell kinase, p59-HCK/p60-HCK, p59Hck, p61Hck, HCK
Tested Applications
WB, IHC-P, Flow
Protein ID
20141296
Physical Properties
Liquid