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NEIL2 Antibody

CAT: 0223-58-223Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-58-223Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
NEIL2 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction (Bandaru et al., 2002 [PubMed 12509226])
NCBI Gene ID
252969
Swiss Prot
Q969S2
Accession Number
Q969S2
Host
Rabbit
Reactivity
Human
Immunogen
This NEIL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 67-96 amino acids from the N-terminal region of human NEIL2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
37 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
NEIL2
NCBI Official Name
Endonuclease 8-like 2
NCBI Organism
Homo sapiens
Background Reference 01
Briggs, F.B., et al. Am. J. Epidemiol. 172 (2) :217-224 (2010)
Background Reference 02
Monsees, G.M., et al. Breast Cancer Res. Treat. (2010) In press :
Background Reference 03
Grin, I.R., et al. Biochem. Biophys. Res. Commun. 394 (1) :100-105 (2010)
Background Reference 04
Kinslow, C.J., et al. Genes Chromosomes Cancer 47 (11) :923-932 (2008)
Other Product Names
Endonuclease 8-like 2, 322-, DNA glycosylase/AP lyase Neil2, DNA- (apurinic or apyrimidinic site) lyase Neil2, Endonuclease VIII-like 2, Nei homolog 2, NEH2, Nei-like protein 2, NEIL2
Tested Applications
WB
Protein ID
56404653
Physical Properties
Liquid

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