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NEIL3 Antibody

CAT: 0223-60-519Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-60-519Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
NEIL3 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction (Bandaru et al., 2002 [PubMed 12509226]) .
NCBI Gene ID
55247
Swiss Prot
Q8TAT5
Accession Number
Q8TAT5
Host
Rabbit
Reactivity
Human
Immunogen
This NEIL3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 292-320 amino acids from the Central region of human NEIL3.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
68 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
NEIL3
NCBI Official Name
Endonuclease 8-like 3
NCBI Organism
Homo sapiens
Background Reference 01
Krokeide, S.Z., et al. Protein Expr. Purif. 65 (2) :160-164 (2009)
Background Reference 02
Takao, M., et al. Genes Cells 14 (2) :261-270 (2009)
Background Reference 03
Dallosso, A.R., et al. Gut 57 (9) :1252-1255 (2008)
Background Reference 04
Bethke, L., et al. J. Natl. Cancer Inst. 100 (4) :270-276 (2008)
Other Product Names
Endonuclease 8-like 3, 322-, DNA glycosylase FPG2, DNA glycosylase/AP lyase Neil3, Endonuclease VIII-like 3, Nei-like protein 3, NEIL3
Tested Applications
WB
Protein ID
302393810
Physical Properties
Liquid

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