CDH10 Antibody

• Background:

  CDH10 is a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. The extracellular domain consists of 5 subdomains, each containing a cadherin motif, and appears to determine the specificity of the protein's homophilic cell adhesion activity. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. This particular cadherin is predominantly expressed in brain and is putatively involved in synaptic adhesions, axon outgrowth and guidance.

• NCBI Gene ID:

  1008

• Swiss Prot:

  Q9Y6N8

• Accession Number:

  Q9Y6N8

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This CDH10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 25-55 amino acids from the N-terminal region of human CDH10.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Neuroscience, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  88 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  CDH10

• NCBI Official Name:

  Cadherin-10

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Kools, P., FEBS Lett. 452 (3), 328-334 (1999)

• Other Product Names:

  Cadherin-10, T2-cadherin, CDH10

• Tested Applications:

  WB, IHC-P, Flow

• Protein ID:

  116241276

• Physical Properties:

  Liquid