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CDH12 Antibody

CAT: 0223-57-950Size: 400 µLDry Ice: NoHazardous: No
CAT#: 57-950Size: 400 µL
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PRICE
AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
CDH12 is a type II classical cadherin from the cadherin superfamily of integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. This particular cadherin appears to be expressed specifically in the brain and its temporal pattern of expression would be consistent with a role during a critical period of neuronal development, perhaps specifically during synaptogenesis.
NCBI Gene ID
1010
Swiss Prot
P55289
Accession Number
P55289
Host
Rabbit
Reactivity
Human
Immunogen
This CDH12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 62-90 amino acids from the N-terminal region of human CDH12.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
88 kDa
Fragment
Rabbit Ig
Symbol
CDH12
NCBI Official Name
Cadherin-12
NCBI Organism
Homo sapiens
Background Reference 01
Shimoyama, Y., Biochem. J. 349 (PT 1), 159-167 (2000)
Background Reference 02
Chalmers, I.J., Genomics 57 (1), 160-163 (1999)
Background Reference 03
Kremmidiotis, G., Genomics 49 (3), 467-471 (1998)
Background Reference 04
Selig, S., Proc. Natl. Acad. Sci. U.S.A. 94 (6), 2398-2403 (1997)
Other Product Names
Cadherin-12, Brain cadherin, BR-cadherin, Neural type cadherin 2, N-cadherin 2, CDH12
Tested Applications
WB, IHC-P
Protein ID
158937438
Physical Properties
Liquid

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