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CDH16 Antibody

CAT: 0223-57-241Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-57-241Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. Mapped to a previously identified cluster of cadherin genes on chromosome 16q22.1, the gene localizes with superfamily members CDH1, CDH3, CDH5, CDH8 and CDH11. The protein consists of an extracellular domain containing 6 cadherin domains, a transmembrane region and a truncated cytoplasmic domain but lacks the prosequence and tripeptide HAV adhesion recognition sequence typical of most classical cadherins. Expression is exclusively in kidney, where the protein functions as the principal mediator of homotypic cellular recognition, playing a role in the morphogenic direction of tissue development.
NCBI Gene ID
1014
Swiss Prot
O75309
Accession Number
O75309
Host
Rabbit
Reactivity
Human
Immunogen
This CDH16 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 796-824 amino acids from the C-terminal region of human CDH16.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
90 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
CDH16
NCBI Official Name
Cadherin-16
NCBI Organism
Homo sapiens
Background Reference 01
Thedieck, C., et al. J. Mol. Biol. 378 (1) :145-153 (2008)
Background Reference 02
Kuehn, A., et al. Am. J. Surg. Pathol. 31 (10) :1528-1533 (2007)
Background Reference 03
Thedieck, C., et al. Br. J. Cancer 92 (11) :2010-2017 (2005)
Background Reference 04
Hishikawa, K., et al. Biochem. Biophys. Res. Commun. 328 (1) :288-291 (2005)
Other Product Names
Cadherin-16, Kidney-specific cadherin, Ksp-cadherin, CDH16
Tested Applications
WB
Physical Properties
Liquid

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