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CDH11 Antibody

CAT: 0223-59-952Size: 400 µLDry Ice: NoHazardous: No
CAT#: 59-952Size: 400 µL
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PRICE
AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Expression of this particular cadherin in osteoblastic cell lines, and its upregulation during differentiation, suggests a specific function in bone development and maintenance.
NCBI Gene ID
1009
Swiss Prot
P55287
Accession Number
P55287
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This CDH11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 622-650 amino acids from the C-terminal region of human CDH11.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
88 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
CDH11
NCBI Official Name
Cadherin-11
NCBI Organism
Homo sapiens
Background Reference 01
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background Reference 02
Sachdeva, M., et al. Cancer Res. 70 (1) :378-387 (2010)
Background Reference 03
Canova, C., et al. Cancer Res. 69 (7) :2956-2965 (2009)
Background Reference 04
Farina, A.K., et al. PLoS ONE (3), E4797 (2009) :
Other Product Names
Cadherin-11, OSF-4, Osteoblast cadherin, OB-cadherin, CDH11
Tested Applications
WB
Protein ID
146345381
Physical Properties
Liquid

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