Mouse Map3k7 Antibody

CAT: 0223-57-351Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-57-351Size:400 µL
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Component of a protein kinase signal transduction cascade. Mediator of TRAF6 and TGF-beta signal transduction. Activates IKBKB and MAPK8 in response to TRAF6 signaling. Stimulates NF-kappa-B activation and the p38 MAPK pathway. In osmotic stress signaling, plays a major role in the activation of MAPK8/JNK, but not that of NF-kappa-B.
NCBI Gene ID
26409
Swiss Prot
Q62073
Accession Number
Q62073
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This Mouse Map3k7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 131-160 amino acids from the N-terminal region of mouse Map3k7.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Immunology, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
64 kDa
Fragment
Rabbit Ig
Symbol
Map3k7
NCBI Official Name
Mitogen-activated protein kinase kinase kinase 7
NCBI Organism
Mus musculus
Background Reference 01
Kajino-Sakamoto, R., et al. J. Immunol. 185 (8) :4729-4737 (2010)
Background Reference 02
Wu, Z.H., et al. Mol. Cell 40 (1) :75-86 (2010)
Background Reference 03
Scholz, R., et al. J. Biol. Chem. 285 (33) :25753-25766 (2010)
Background Reference 04
Greenblatt, M.B., et al. J. Clin. Invest. 120 (7) :2457-2473 (2010)
Other Product Names
Mitogen-activated protein kinase kinase kinase 7, Transforming growth factor-beta-activated kinase 1, TGF-beta-activated kinase 1, Map3k7, Tak1
Tested Applications
WB, IHC-P
Physical Properties
Liquid

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