Mouse Map2k3 Antibody

• Background:

  Dual specificity kinase. Is activated by cytokines and environmental stress in vivo. Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in the MAP kinase p38 (By similarity) .

• NCBI Gene ID:

  26397

• Swiss Prot:

  O09110

• Accession Number:

  O09110

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  This Mouse Map2k3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 132-160 amino acids from the Central region of mouse Map2k3.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Immunology, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  39 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  Map2k3

• NCBI Official Name:

  Dual specificity mitogen-activated protein kinase kinase 3

• NCBI Organism:

  Mus musculus

• Background Reference 01:

  Yang, Z., et al. J. Immunol. 185 (10) :6205-6213 (2010)

• Background Reference 02:

  Remy, G., et al. Cell. Signal. 22 (4) :660-667 (2010)

• Background Reference 03:

  Behren, A., et al. Oncogene 29 (10) :1519-1530 (2010)

• Background Reference 04:

  Nagelin, M.H., et al. J. Biol. Chem. 284 (45) :31303-31314 (2009)

• Other Product Names:

  Dual specificity mitogen-activated protein kinase kinase 3, MAP kinase kinase 3, MAPKK 3, MAPK/ERK kinase 3, MEK 3, Map2k3, Mkk3, Prkmk3

• Tested Applications:

  WB

• Physical Properties:

  Liquid