Mouse Mapk14 Antibody

CAT: 0223-58-339Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-58-339Size:400 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Responds to activation by environmental stress, pro-inflammatory cytokines and lipopolysaccharide (LPS) by phosphorylating a number of transcription factors, such as ELK1 and ATF2 and several downstream kinases, such as MAPKAPK2 and MAPKAPK5. Plays a critical role in the production of some cytokines, for example IL-6. Required in mid-fetal development for the growth of embryo-derived blood vessels in the labyrinth layer of the placenta. Also plays an essential role in developmental and stress-induced erythropoiesis, through regulation of EPO gene expression.
NCBI Gene ID
26416
Swiss Prot
P47811
Accession Number
P47811
Host
Rabbit
Reactivity
Human
Immunogen
This Mouse Mapk14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 26-53 amino acids from the N-terminal region of mouse Mapk14.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Immunology, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
41 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
Mapk14
NCBI Official Name
Mitogen-activated protein kinase 14
NCBI Organism
Mus musculus
Background Reference 01
Pan, W.W., et al. J. Biol. Chem. 285 (45) :34348-34354 (2010)
Background Reference 02
Menon, M.B., et al. J. Biol. Chem. 285 (43) :33242-33251 (2010)
Background Reference 03
Chandrakesan, P., et al. J. Biol. Chem. 285 (43) :33485-33498 (2010)
Background Reference 04
Ferreiro, I., et al. J. Biol. Chem. 285 (41) :31819-31828 (2010)
Other Product Names
Mitogen-activated protein kinase 14, MAP kinase 14, MAPK 14, CRK1, Mitogen-activated protein kinase p38 alpha, MAP kinase p38 alpha, Mapk14, Crk1, Csbp1, Csbp2
Tested Applications
WB
Physical Properties
Liquid

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