Mouse Mapk3 Antibody

• Background:

  Involved in both the initiation and regulation of meiosis, mitosis, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors such as ELK-1. Phosphorylates EIF4EBP1; required for initiation of translation. Phosphorylates microtubule-associated protein 2 (MAP2) and heat shock factor protein 4 (HSF4) (By similarity) . Phosphorylates SPZ1.

• NCBI Gene ID:

  26417

• Swiss Prot:

  Q63844

• Accession Number:

  Q63844

• Host:

  Rabbit

• Reactivity:

  Mouse

• Immunogen:

  This Mouse Mapk3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 353-380 amino acids from the C-terminal region of mouse Mapk3.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Cell Cycle, Neuroscience, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  43 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  Mapk3

• NCBI Official Name:

  Mitogen-activated protein kinase 3

• NCBI Organism:

  Mus musculus

• Background Reference 01:

  Chen, W., et al. Biochem. Biophys. Res. Commun. 401 (3) :339-343 (2010)

• Background Reference 02:

  Chandrakesan, P., et al. J. Biol. Chem. 285 (43) :33485-33498 (2010)

• Background Reference 03:

  Alter, B.J., et al. J. Neurosci. 30 (34) :11537-11547 (2010)

• Background Reference 04:

  Spruce, T., et al. Dev. Cell 19 (2) :207-219 (2010)

• Other Product Names:

  Mitogen-activated protein kinase 3, MAP kinase 3, MAPK 3, ERT2, Extracellular signal-regulated kinase 1, ERK-1, Insulin-stimulated MAP2 kinase, MAP kinase isoform p44, p44-MAPK, MNK1, Microtubule-associated protein 2 kinase, p44-ERK1, Mapk3, Erk1, Prkm3

• Tested Applications:

  WB, IHC-P, Flow

• Physical Properties:

  Liquid