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UBP46 Antibody

CAT: 0223-57-525Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-57-525Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Modification of cellular proteins by ubiquitin is an essential regulatory mechanism controlled by the coordinated action of multiple ubiquitin-conjugating and deubiquitinating enzymes. USP46 belongs to a large family of cysteine proteases that function as deubiquitinating enzymes (Quesada et al., 2004 [PubMed 14715245]) .
NCBI Gene ID
64854
Swiss Prot
P62068
Accession Number
P62068
Host
Rabbit
Reactivity
Human
Immunogen
This UBP46 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 241-269 amino acids from the C-terminal region of human UBP46.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Zebrafish, Mouse
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
42 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
USP46
NCBI Official Name
Ubiquitin carboxyl-terminal hydrolase 46
NCBI Organism
Homo sapiens
Background Reference 01
Kushima, I., et al. J. Hum. Genet. 55 (3) :133-136 (2010)
Background Reference 02
Cohn, M.A., et al. J. Biol. Chem. 284 (8) :5343-5351 (2009)
Background Reference 03
Zemunik, T., et al. Croat. Med. J. 50 (1) :23-33 (2009)
Background Reference 04
Quesada, V., et al. Biochem. Biophys. Res. Commun. 314 (1) :54-62 (2004)
Other Product Names
Ubiquitin carboxyl-terminal hydrolase 46, Deubiquitinating enzyme 46, Ubiquitin thioesterase 46, Ubiquitin-specific-processing protease 46, USP46
Tested Applications
WB
Protein ID
49065850
Physical Properties
Liquid

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