MAP2K5 Antibody

CAT: 0223-63-281Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-63-281Size:400 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
MAP2K5 is a dual specificity protein kinase that belongs to the MAP kinase kinase family. It specifically interacts with and activates MAPK7/ERK5. This kinase itself can be phosphorylated and activated by MAP3K3/MEKK3, as well as by atypical protein kinase C isoforms (aPKCs) . The signal cascade mediated by MAP2K5 is involved in growth factor stimulated cell proliferation and muscle cell differentiation.
NCBI Gene ID
5607
Swiss Prot
Q13163
Accession Number
Q13163
Host
Rabbit
Reactivity
Human
Immunogen
This MAP2K5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 127-156 amino acids from human MAP2K5.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
50 kDa
Fragment
Rabbit Ig
Symbol
MAP2K5
NCBI Official Name
Dual specificity mitogen-activated protein kinase kinase 5
NCBI Organism
Homo sapiens
Background Reference 01
Raviv, Z., J. Cell. Sci. 117 (PT 9), 1773-1784 (2004)
Background Reference 02
Kato, Y., EMBO J. 16 (23), 7054-7066 (1997)
Background Reference 03
English, J.M., J. Biol. Chem. 274 (44), 31588-31592 (1999)
Other Product Names
Dual specificity mitogen-activated protein kinase kinase 5, MAP kinase kinase 5, MAPKK 5, MAPK/ERK kinase 5, MEK 5, MAP2K5, MEK5, MKK5, PRKMK5
Tested Applications
WB, IHC-P
Protein ID
118572669
Physical Properties
Liquid

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