MAP2K5 Antibody

• Background:

  MAP2K5 is a dual specificity protein kinase that belongs to the MAP kinase kinase family. It specifically interacts with and activates MAPK7/ERK5. This kinase itself can be phosphorylated and activated by MAP3K3/MEKK3, as well as by atypical protein kinase C isoforms (aPKCs) . The signal cascade mediated by MAP2K5 is involved in growth factor stimulated cell proliferation and muscle cell differentiation.

• NCBI Gene ID:

  5607

• Swiss Prot:

  Q13163

• Accession Number:

  Q13163

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This MAP2K5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 127-156 amino acids from human MAP2K5.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  50 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  MAP2K5

• NCBI Official Name:

  Dual specificity mitogen-activated protein kinase kinase 5

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Raviv, Z., J. Cell. Sci. 117 (PT 9), 1773-1784 (2004)

• Background Reference 02:

  Kato, Y., EMBO J. 16 (23), 7054-7066 (1997)

• Background Reference 03:

  English, J.M., J. Biol. Chem. 274 (44), 31588-31592 (1999)

• Other Product Names:

  Dual specificity mitogen-activated protein kinase kinase 5, MAP kinase kinase 5, MAPKK 5, MAPK/ERK kinase 5, MEK 5, MAP2K5, MEK5, MKK5, PRKMK5

• Tested Applications:

  WB, IHC-P

• Protein ID:

  118572669

• Physical Properties:

  Liquid