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MAP2K5 Antibody

CAT: 0223-22-583Size: 100 µLDry Ice: NoHazardous: No
CAT#:0223-22-583Size:100 µL
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Background
The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically interacts with and activates MAPK7/ERK5. This kinase itself can be phosphorylated and activated by MAP3K3/MEKK3, as well as by atypical protein kinase C isoforms (aPKCs) . The signal cascade mediated by this kinase is involved in growth factor stimulated cell proliferation and muscle cell differentiation. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been described.
NCBI Gene ID
5607
Swiss Prot
Q13163
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of human MAP2K5 (NP_660143.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Immunology, Signal Transduction
Purification
Affinity purification
Positive Control
NCI-H460
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 50kDa
Fragment
IgG
Symbol
MAP2K5
Positive Control 2
BT-474
Positive Control 3
Mouse liver
Positive Control 4
Rat liver
Positive Control 5
Rat kidney
NCBI Official Name
Dual specificity mitogen-activated protein kinase kinase 5
NCBI Organism
Homo sapiens
Other Product Names
Dual specificity mitogen-activated protein kinase kinase 5, MAP kinase kinase 5, MAPKK 5, MAPK/ERK kinase 5, MEK 5, MAP2K5, MEK5, MKK5, PRKMK5
Tested Applications
WB, IHC, IF
Physical Properties
Liquid

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MBS7124087-01MAP2K5 Antibody

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