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Mouse Pan3 Antibody

CAT: 0223-57-362Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-57-362Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Functions in cytoplasmic mRNA decay. As part of the Pan nuclease complex, recruits polyadenylate-binding protein which in turn stimulates PAN2 nuclease activity (By similarity) .
NCBI Gene ID
72587
Swiss Prot
Q640Q5
Accession Number
Q640Q5
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This Mouse Pan3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 727-755 amino acids from the C-terminal region of mouse Pan3.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
90 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
Pan3
NCBI Official Name
PAB-dependent poly (A) -specific ribonuclease subunit PAN3 {ECO:0000255|HAMAP-Rule:MF_03181}
NCBI Organism
Mus musculus
Background Reference 01
Zheng, D., et al. J. Cell Biol. 182 (1) :89-101 (2008)
Background Reference 02
Siddiqui, N., et al. J. Biol. Chem. 282 (34) :25067-25075 (2007)
Background Reference 03
Nishimura, M., et al. DNA Res. 11 (5) :315-323 (2004)
Background Reference 04
Zambrowicz, B.P., et al. Proc. Natl. Acad. Sci. U.S.A. 100 (24) :14109-14114 (2003)
Other Product Names
PAB-dependent poly (A) -specific ribonuclease subunit PAN3 {ECO:0000255|HAMAP-Rule:MF_03181}, PAB1P-dependent poly (A) -nuclease {ECO:0000255|HAMAP-Rule:MF_03181}, PAN deadenylation complex subunit 3 {ECO:0000255|HAMAP-Rule:MF_03181}, Pan3
Tested Applications
WB
Physical Properties
Liquid

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