PAN3 Antibody

• Background:

  PAN3 is functions in cytoplasmic mRNA decay. It is as part of the Pan nuclease complex, recruits polyadenylate-binding protein which in turn stimulates PAN2 nuclease activity.

• NCBI Gene ID:

  255967

• Swiss Prot:

  Q58A45

• Accession Number:

  Q58A45

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This PAN3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 771-799 amino acids from the C-terminal region of human PAN3.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Mouse

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  96 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  PAN3

• NCBI Official Name:

  PAB-dependent poly (A) -specific ribonuclease subunit PAN3 {ECO:0000255|HAMAP-Rule:MF_03181}

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Uchida, N., et al. J. Biol. Chem. 279 (2) :1383-1391 (2004)

• Other Product Names:

  PAB-dependent poly (A) -specific ribonuclease subunit PAN3 {ECO:0000255|HAMAP-Rule:MF_03181}, PAB1P-dependent poly (A) -nuclease {ECO:0000255|HAMAP-Rule:MF_03181}, PAN deadenylation complex subunit 3 {ECO:0000255|HAMAP-Rule:MF_03181}, hPan3, PAN3 {ECO:0000255|HAMAP-Rule:MF_03181}

• Tested Applications:

  WB, IHC-P, Flow

• Protein ID:

  341942213

• Physical Properties:

  Liquid