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PAN2 Antibody

CAT: 0223-58-634Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-58-634Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a deadenylase that functions as the catalytic subunit of the polyadenylate binding protein dependent poly (A) nuclease complex. The encoded protein is a magnesium dependent 3' to 5' exoribonuclease that is involved in the degradation of cytoplasmic mRNAs. Alternate splicing results in multiple transcript variants.
NCBI Gene ID
9924
Swiss Prot
Q504Q3
Accession Number
Q504Q3
Host
Rabbit
Reactivity
Human
Immunogen
This PAN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 860-888 amino acids from the C-terminal region of human PAN2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Chicken, Mouse, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
135 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
PAN2
NCBI Official Name
PAB-dependent poly (A) -specific ribonuclease subunit PAN2 {ECO:0000255|HAMAP-Rule:MF_03182}
NCBI Organism
Homo sapiens
Background Reference 01
Bailey, S.D., et al. Diabetes Care (2010) In press :
Background Reference 02
Talmud, P.J., et al. Am. J. Hum. Genet. 85 (5) :628-642 (2009)
Background Reference 03
Funakoshi, Y., et al. Genes Dev. 21 (23) :3135-3148 (2007)
Background Reference 04
Ezzeddine, N., et al. Mol. Cell. Biol. 27 (22) :7791-7801 (2007)
Other Product Names
PAB-dependent poly (A) -specific ribonuclease subunit PAN2 {ECO:0000255|HAMAP-Rule:MF_03182}, hPan2, 31134 {ECO:0000255|HAMAP-Rule:MF_03182}, Inactive ubiquitin carboxyl-terminal hydrolase 52 {ECO:0000255|HAMAP-Rule:MF_03182}, PAB1P-dependent poly (A) -nuclease {ECO:0000255|HAMAP-Rule:MF_03182}, PAN deadenylation complex catalytic subunit 2 {ECO:0000255|HAMAP-Rule:MF_03182}, PAN2 {ECO:0000255|HAMAP-Rule:MF_03182}, KIAA0710, USP52
Tested Applications
WB
Protein ID
296439280
Physical Properties
Liquid

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