GUCY2F Antibody

• Background:

  The protein encoded by this gene is a guanylyl cyclase found predominantly in photoreceptors in the retina. The encoded protein is thought to be involved in resynthesis of cGMP after light activation of the visual signal transduction cascade, allowing a return to the dark state. This protein is a single-pass type I membrane protein. Defects in this gene may be a cause of X-linked retinitis pigmentosa.

• NCBI Gene ID:

  2986

• Swiss Prot:

  P51841

• Host:

  Rabbit

• Reactivity:

  Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 250-460 of human GUCY2F (NP_001513.2) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  Mouse eye

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 125kDa

• Fragment:

  IgG

• Symbol:

  GUCY2F

• NCBI Official Name:

  Retinal guanylyl cyclase 2

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Retinal guanylyl cyclase 2, RETGC-2, Guanylate cyclase 2F, retinal, Guanylate cyclase F, GC-F, Rod outer segment membrane guanylate cyclase 2, ROS-GC2, GUCY2F, GUC2F, RETGC2

• Tested Applications:

  WB, IF

• Physical Properties:

  Liquid