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GUCY2F Antibody

CAT: 0223-58-840Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-58-840Size:400 µL
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Background
The protein encoded by this gene is a guanylyl cyclase found predominantly in photoreceptors in the retina. The encoded protein is thought to be involved in resynthesis of cGMP after light activation of the visual signal transduction cascade, allowing a return to the dark state. This protein is a single-pass type I membrane protein. Defects in this gene may be a cause of X-linked retinitis pigmentosa.
NCBI Gene ID
2986
Swiss Prot
P51841
Accession Number
P51841
Host
Rabbit
Reactivity
Human
Immunogen
This GUCY2F antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 828-856 amino acids from the C-terminal region of human GUCY2F.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
125 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
GUCY2F
NCBI Official Name
Retinal guanylyl cyclase 2
NCBI Organism
Homo sapiens
Background Reference 01
Blackford, A., et al. Cancer Res. 69 (8) :3681-3688 (2009)
Background Reference 02
Helten, A., et al. J. Neurochem. 103 (4) :1439-1446 (2007)
Background Reference 03
Wood, L.D., et al. Hum. Mutat. 27 (10) :1060-1061 (2006)
Background Reference 04
Ross, M.T., et al. Nature 434 (7031) :325-337 (2005)
Other Product Names
Retinal guanylyl cyclase 2, RETGC-2, Guanylate cyclase 2F, retinal, Guanylate cyclase F, GC-F, Rod outer segment membrane guanylate cyclase 2, ROS-GC2, GUCY2F, GUC2F, RETGC2
Tested Applications
WB
Protein ID
311033391
Physical Properties
Liquid

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