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HDAC7 Antibody

CAT: 0223-57-176Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-57-176Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous to mouse HDAC7 gene whose protein promotes repression mediated via the transcriptional corepressor SMRT. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
NCBI Gene ID
51564
Swiss Prot
Q8WUI4
Accession Number
Q8WUI4
Host
Rabbit
Reactivity
Human
Immunogen
This HDAC7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 846-875 amino acids from the C-terminal region of human HDAC7.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
103 kDa
Fragment
Rabbit Ig
Symbol
HDAC7
NCBI Official Name
Histone deacetylase 7
NCBI Organism
Homo sapiens
Background Reference 01
Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)
Background Reference 02
Margariti, A., et al. Circ. Res. 106 (7) :1202-1211 (2010)
Background Reference 03
Hutt, D.M., et al. Nat. Chem. Biol. 6 (1) :25-33 (2010)
Background Reference 04
Malik, S., et al. Mol. Cell. Biol. 30 (2) :399-412 (2010)
Other Product Names
Histone deacetylase 7, HD7, Histone deacetylase 7A, HD7a, HDAC7, HDAC7A
Tested Applications
WB, IHC-P
Protein ID
30913097
Physical Properties
Liquid

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