UNC5C Antibody

• Background:

  This gene product belongs to the UNC-5 family of netrin receptors. Netrins are secreted proteins that direct axon extension and cell migration during neural development. They are bifunctional proteins that act as attractants for some cell types and as repellents for others, and these opposite actions are thought to be mediated by two classes of receptors. The UNC-5 family of receptors mediate the repellent response to netrin; they are transmembrane proteins containing 2 immunoglobulin (Ig) -like domains and 2 type I thrombospondin motifs in the extracellular region.

• NCBI Gene ID:

  8633

• Swiss Prot:

  O95185

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 300-360 of human UNC5C (NP_003719.3) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Apoptosis, Cell Cycle, Neuroscience

• Purification:

  Affinity purification

• Positive Control:

  SH-SY5Y

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 103kDa

• Fragment:

  IgG

• Applications Notes:

  WB: 1:500 - 1:2000

• Symbol:

  UNC5C

• Positive Control 2:

  293T

• Positive Control 3:

  Mouse brain

• Positive Control 4:

  Mouse lung

• Positive Control 5:

  Rat brain

• NCBI Official Name:

  Unc-5 homolog C (C. elegans)

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Unc5C, unc5 (C.elegans homolog) c, homolog of C. elegans transmembrane receptor Unc5, UNC5H3, unc-5 homolog C (C. elegans), UNC5C

• Tested Applications:

  WB

• Physical Properties:

  Liquid