UNC5C Antibody

• Background:

  UNC5C belongs to the UNC-5 family of netrin receptors. Netrins are secreted proteins that direct axon extension and cell migration during neural development. They are bifunctional proteins that act as attractants for some cell types and as repellents for others, and these opposite actions are thought to be mediated by two classes of receptors. The UNC-5 family of receptors mediate the repellent response to netrin; they are transmembrane proteins containing 2 immunoglobulin (Ig) -like domains and 2 type I thrombospondin motifs in the extracellular region.

• NCBI Gene ID:

  8633

• Swiss Prot:

  O95185

• Accession Number:

  O95185

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This UNC5C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 188-217 amino acids from the Central region of human UNC5C.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle, Neuroscience

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Rat

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  103 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  UNC5C

• NCBI Official Name:

  Netrin receptor UNC5C

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Hibi, K., et.al., WorldSurg 33 (5), 1053-1057 (2009)

• Other Product Names:

  Netrin receptor UNC5C, Protein unc-5 homolog 3, Protein unc-5 homolog C, UNC5C, UNC5H3

• Tested Applications:

  WB, IHC-P, Flow

• Physical Properties:

  Liquid