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UNC5D Polyclonal Antibody

CAT: 0749-ABP60858-01Size: 30 µLDry Ice: NoHazardous: No
CAT#:0749-ABP60858-01Size:30 µL
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Background
Receptor for the netrin NTN4 that promotes neuronal cell survival. Plays a role in cell-cell adhesion and cell guidance. Receptor for netrin involved in cell migration. Plays a role in axon guidance by mediating axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding. May play a role in apoptosis in response to DNA damage. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand (PubMed: 24519068) . Mediates cell-cell adhesion via its interaction with FLRT3 on an adjacent cell.
Description
Rabbit Anti-UNC5D Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
Netrin receptor UNC5D; Protein unc-5 homolog 4; Protein unc-5 homolog D
Gene ID
137970
Accession Number
Q6UXZ4
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from part region of human UNC5D protein at amino acid sequence of 160-240
Clonality
Polyclonal
Tag
UNC5D
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
104kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of UNC5D protein
Observed Molecular Weight
104
Formulation
Liquid solution
Buffer pH
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000
Other Product Names
Netrin receptor UNC5D; Protein unc-5 homolog 4; Protein unc-5 homolog D
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q6UXZ4
Isotype
Rabbit IgG

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