UNC5B Antibody

• Background:

  This gene encodes a member of the netrin family of receptors. This particular protein mediates the repulsive effect of netrin-1 and is a vascular netrin receptor. This encoded protein is also in a group of proteins called dependence receptors (DpRs) which are involved in pro- and anti-apoptotic processes. Many DpRs are involved in embryogenesis and in cancer progression. Two alternatively spliced transcript variants have been described for this gene.

• NCBI Gene ID:

  219699

• Swiss Prot:

  Q8IZJ1

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 290-377 of human UNC5B (NP_734465.2) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Apoptosis, Cell Cycle, Neuroscience, Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  U-87MG

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 104kDa

• Fragment:

  IgG

• Symbol:

  UNC5B

• Positive Control 2:

  A-549

• Positive Control 3:

  293T

• Positive Control 4:

  Mouse brain

• Positive Control 5:

  Mouse lung

• Positive Control 6:

  Mouse kidney

• NCBI Official Name:

  Unc-5 homolog B (C. elegans)

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  6330415E02Rik, A630020F16, D10Bwg0792e, netrin receptor UNC5B, protein unc-5 homolog 2, protein unc-5 homolog B, unc5 homolog 2, unc-5 homolog 2, unc-5 homolog B (C. elegans), Unc5b, Unc5h2 , P53RDL1, UNC5H2, UNQ1883/PRO4326

• Tested Applications:

  WB, IF

• Physical Properties:

  Liquid