SENP1 Antibody

• Background:

  SENP1 is a protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO1, SUMO2 and SUMO3 to their mature forms and deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins. SENP deconjugates SUMO1 from HIPK2 and from HDAC1, which decreases the transcriptional repression activity of the latter.

• NCBI Gene ID:

  29843

• Swiss Prot:

  Q9P0U3

• Accession Number:

  Q9P0U3

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This SENP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 28-59 amino acids from the N-terminal region of human SENP1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle

• Purification:

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  73 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  SENP1

• NCBI Official Name:

  Sentrin-specific protease 1

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Gong, L., et al., J. Biol. Chem. 275 (5) :3355-3359 (2000) . Bailey, D., et al., J. Gen. Virol. 83 (Pt 12), 2951-2964 (2002) .

• Other Product Names:

  Sentrin-specific protease 1, Sentrin/SUMO-specific protease SENP1, SENP1

• Tested Applications:

  WB, IHC-P

• Protein ID:

  215273882

• Physical Properties:

  Liquid