SENP6 Antibody

• Background:

  SENP6 (SUSP1) is a protease that deconjugates SUMO1, SUMO2 and SUMO3 from targeted proteins. This protein does not seem to be involved in the processing of full-length SUMO proteins to their mature conjugatable forms. SENP6 deconjugates SUMO1 from RXRA, leading to transcriptional activation. It may act preferentially on substrates containing 3 or more SUMO2 or SUMO3 moieties.

• NCBI Gene ID:

  26054

• Swiss Prot:

  Q9GZR1

• Accession Number:

  Q9GZR1

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This SENP6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1081-1112 amino acids from the C-terminal region of human SENP6.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle

• Purification:

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  126 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  SENP6

• NCBI Official Name:

  Sentrin-specific protease 6

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Ota, T., et al., Nat. Genet. 36 (1) :40-45 (2004) .

• Background Reference 02:

  Strausberg, R.L., et al., Proc. Natl. Acad. Sci. U.S.A. 99 (26) :16899-16903 (2002) .

• Background Reference 03:

  Kim, K.I., et al., J. Biol. Chem. 275 (19) :14102-14106 (2000) .

• Other Product Names:

  Sentrin-specific protease 6, SUMO-1-specific protease 1, Sentrin/SUMO-specific protease SENP6, SENP6, KIAA0797, SSP1, SUSP1

• Tested Applications:

  WB, IHC-P

• Protein ID:

  119370526

• Physical Properties:

  Liquid