SENP2 Antibody

CAT: 0223-56-352Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-56-352Size:400 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
SUMO is a small ubiquitin-like protein that can be covalently conjugated to other proteins. SENP2 is one of a group of enzymes that process newly synthesized SUMO1, SUMO2, and SUMO3 into the conjugatable mature forms and catalyze the deconjugation of these same SUMO proteins from their targeted substrates. SENP2 may also down-regulate CTNNB1 levels and thereby modulate the Wnt pathway.
NCBI Gene ID
59343
Swiss Prot
Q9HC62
Accession Number
Q9HC62
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This SENP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 502-533 amino acids from the C-terminal region of human SENP2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
68 kDa
Fragment
Rabbit Ig
Symbol
SENP2
NCBI Official Name
Sentrin-specific protease 2
NCBI Organism
Homo sapiens
Background Reference 01
Ota, T., et al., Nat. Genet. 36 (1) :40-45 (2004) .
Background Reference 02
Nakajima, D., et al., DNA Res. 9 (3) :99-106 (2002) .
Background Reference 03
Zhang, H., et al., Mol. Cell. Biol. 22 (18) :6498-6508 (2002) .
Background Reference 04
Hang, J., et al., J. Biol. Chem. 277 (22) :19961-19966 (2002) .
Other Product Names
Sentrin-specific protease 2, Axam2, SMT3-specific isopeptidase 2, Smt3ip2, Sentrin/SUMO-specific protease SENP2, SENP2, KIAA1331
Tested Applications
WB, IHC-P
Protein ID
143811458
Physical Properties
Liquid

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