SENP5 Antibody

CAT: 0223-57-708Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-57-708Size:400 µL
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The reversible posttranslational modification of proteins by the addition of small ubiquitin-like SUMO proteins (see SUMO1; MIM 601912) is required for numerous biologic processes. SUMO-specific proteases, such as SENP5, are responsible for the initial processing of SUMO precursors to generate a C-terminal diglycine motif required for the conjugation reaction. They also have isopeptidase activity for the removal of SUMO from high molecular mass SUMO conjugates (Di Bacco et al., 2006 [PubMed 16738315]) .
NCBI Gene ID
205564
Swiss Prot
Q96HI0
Accession Number
Q96HI0
Host
Rabbit
Reactivity
Human
Immunogen
This SENP5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 718-747 amino acids from the C-terminal region of human SENP5.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Monkey, Mouse
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
87 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
SENP5
NCBI Official Name
Sentrin-specific protease 5
NCBI Organism
Homo sapiens
Background Reference 01
Yun, C., et al. J. Cell Biol. 183 (4) :589-595 (2008)
Background Reference 02
Ding, X., et al. Oncol. Rep. 20 (5) :1041-1045 (2008)
Background Reference 03
Gong, L., et al. J. Biol. Chem. 281 (23) :15869-15877 (2006)
Background Reference 04
Di Bacco, A., et al. Mol. Cell. Biol. 26 (12) :4489-4498 (2006)
Other Product Names
Sentrin-specific protease 5, Sentrin/SUMO-specific protease SENP5, SENP5
Tested Applications
WB
Protein ID
296452962
Physical Properties
Liquid

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