SENP2 Antibody

• Background:

  SUMO is a small ubiquitin-like protein that can be covalently conjugated to other proteins. SENP2 is one of a group of enzymes that process newly synthesized SUMO1, SUMO2, and SUMO3 into the conjugatable mature forms and catalyze the deconjugation of these same SUMO proteins from their targeted substrates. SENP2 may also down-regulate CTNNB1 levels and thereby modulate the Wnt pathway.

• NCBI Gene ID:

  59343

• Swiss Prot:

  Q9HC62

• Accession Number:

  Q9HC62

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This SENP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 502-533 amino acids from the C-terminal region of human SENP2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle

• Purification:

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  68 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  SENP2

• NCBI Official Name:

  Sentrin-specific protease 2

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Zhang, H., et al., Mol. Cell. Biol. 22 (18) :6498-6508 (2002) .

• Background Reference 02:

  Hang, J., et al., J. Biol. Chem. 277 (22) :19961-19966 (2002) .

• Background Reference 03:

  Nishida, T., et al., J. Biol. Chem. 276 (42) :39060-39066 (2001) .

• Other Product Names:

  Sentrin-specific protease 2, Axam2, SMT3-specific isopeptidase 2, Smt3ip2, Sentrin/SUMO-specific protease SENP2, SENP2, KIAA1331

• Tested Applications:

  WB, IHC-P

• Protein ID:

  143811458

• Physical Properties:

  Liquid