Products for Research Use Only
RegisterLogin

GITRL Antibody

CAT: 0223-36-221Size: 100 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0223-36-221Size:100 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
GITRL is expressed on dendritic cells (DC), monocytes, macrophages, B cells, activated T cells, endothelial cells, osteoclasts and various healthy non-lymphoid tissues (e. g. testis, .) . GITRL is constitutively expressed and released as soluble form by solid tumors and various hematopoietic malignancies. GITRL causes differentiation of osteoclasts, activation of macrophages, but also alteration of carcinoma and leukemia cells and influences apoptosis. Binding to GITR is important in regulating T-cell proliferation and TCR-mediated apoptosis. GITRL is implicated in development of autoimmune diseases and in the immune response against infectious pathogens and tumors.
NCBI Gene ID
8995
Swiss Prot
Q9UNG2
Accession Number
13124621
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant human GITRL.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Immunology
Concentration
1 mg/ml
Buffer
Liquid. 0.2um-filtered solution in PBS, pH 7.4. Contains no preservatives.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Stable for at least 6 months after receipt when stored at -20˚ C.
Specificity
Recognizes human GITRL. Detects a band of ~15-17kDa by Western blot. Does not cross-react with mouse GITRL.
Applications Notes
ELISA: (direct and indirect: 1:5,000-1:10,000) . Western Blot: (1:2,000-1:5,000 using ECL. Suggested blocking and dilution buffer is TBST containing 0.05% Tween 20 and 5% skim milk. Suggested incubation time is 1 hour at room temperature) . Optimal conditions must be determined individually for each application.
Symbol
TNFSF18
NCBI Official Name
Tumor necrosis factor (ligand) superfamily, member 18
NCBI Organism
Homo sapiens
Other Product Names
Glucocorticoid-induced TNF Receptor Ligand; AITRL; Activation-inducible TNF-related Ligand; TNFSF18
Tested Applications
ELISA, WB
Protein ID
Q9UNG2
Physical Properties
Liquid

Related Products

CatalogName
90-004GITRL, Soluble Recombinant Protein
36-215GITR Antibody
36-016GITR Antibody [AIT 158D]
24-452GITR Antibody [YGITR765], Rabbit IgG
24-453GITR Antibody [YGITR765], Rat IgG2b
24-622GITR Antibody [DTA-1], Rat IgG2a
24-621GITR Antibody [DTA-1], Rabbit IgG
24-353GITR Antibody [YGITR 860.103.5], Rabbit IgG
91-947GITR Recombinant Protein
97-064GITR Recombinant Protein

Alternative Products

CatalogName
MBS150890-01GITRL Antibody
GWB-25FF9BMouse GITRL Antibody
GTR18048119-01GITRL polyclonal antibody
MBS9233626-01Anti-GITRL Antibody
APR06371GPolyclonal GITRL Antibody
DL98721A-01Rabbit anti-GITRL Antibody
A04408Anti-GITRL TNFSF18 Antibody
GTR18112882-01GITRL Rabbit Polyclonal Antibody
OAAV00371-200UGOAAV00371-200UG - GITRL Antibody
OAAV00370-200UGOAAV00370-200UG - GITRL Antibody

Popular Products