PDHA2 Antibody

• Background:

  The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO (2) . It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) .

• NCBI Gene ID:

  5161

• Swiss Prot:

  P29803

• Accession Number:

  P29803

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This PDHA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 287-314 amino acids from the Central region of human PDHA2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Obesity, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  43 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  PDHA2

• NCBI Official Name:

  Pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Pinheiro, A., et al. Mol. Genet. Metab. 99 (4) :425-430 (2010)

• Background Reference 02:

  Olsen, J.V., et al. Cell 127 (3) :635-648 (2006)

• Background Reference 03:

  Olsen, J.V., et al. Cell 127 (3) :635-648 (2006)

• Background Reference 04:

  Caruso, M., et al. J. Biol. Chem. 276 (48) :45088-45097 (2001)

• Other Product Names:

  Pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial, PDHE1-A type II, PDHA2, PDHAL

• Tested Applications:

  WB, IHC-P

• Physical Properties:

  Liquid