SPIB Antibody

• Background :

  SPIB is a transcription factor in the Ets family. It is found in lymphoid cells and not in monocytes or myeloid cells. SPIB is a regulator of pDC development via its interaction with ID2, E2-2 and BCL2-A1. It promotes E2-2 activity and suppresses Id2 expression to enhance pDC development. It also promotes pDC survival by activation of the antiapoptotic gene BCL2-A1.

• NCBI Gene ID :

  6689

• Swiss Prot :

  Q01892

• Host :

  Rabbit

• Reactivity :

  Human, Mouse

• Immunogen :

  A recombinant protein fragment from the C-terminal half of SPIB was used as the immunogen for this antibody.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Stem Cell, Immunology

• Purification :

  Protein A affinity chromatography

• Concentration :

  0.5 mg/mL

• Buffer :

  PBS with 0.1 mg/ml BSA and 0.05% sodium azide

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Aliquot and Store at -20˚ C. Avoid freez-thaw cycles.

• Fragment :

  IgG

• Symbol :

  SPIB

• NCBI Official Name :

  Spi-B transcription factor (Spi-1/PU.1 related)

• NCBI Organism :

  Homo sapiens

• Other Product Names :

  Spi-B transcription factor, SPI-B

• Tested Applications :

  WB

• Physical Properties :

  Liquid