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SPI1 Antibody

CAT: 0223-58-037Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-58-037Size:400 µL
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Background
This gene encodes an ETS-domain transcription factor that activates gene expression during myeloid and B-lymphoid cell development. The nuclear protein binds to a purine-rich sequence known as the PU-box found near the promoters of target genes, and regulates their expression in coordination with other transcription factors and cofactors. The protein can also regulate alternative splicing of target genes. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
NCBI Gene ID
6688
Swiss Prot
P17947
Accession Number
P17947
Host
Rabbit
Reactivity
Human
Immunogen
This SPI1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 217-246 amino acids from the C-terminal region of human SPI1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse, Pig, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
31 kDa
Fragment
Rabbit Ig
Symbol
SPI1
NCBI Official Name
Transcription factor PU.1
NCBI Organism
Homo sapiens
Background Reference 01
Rimmele, P., et al. Cancer Res. 70 (17) :6757-6766 (2010)
Background Reference 02
Bonadies, N., et al. Oncogene 29 (7) :1062-1072 (2010)
Background Reference 03
Bonadies, N., et al. Blood 115 (2) :331-334 (2010)
Background Reference 04
Desai, S., et al. J. Immunol. 183 (9) :5778-5787 (2009)
Other Product Names
Transcription factor PU1, 31 kDa-transforming protein, SPI1
Tested Applications
WB, IHC-P, IF
Protein ID
60415923
Physical Properties
Liquid

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