SPIC Antibody

• Background:

  This protein Controls the development of red pulp macrophages required for red blood cells recycling and iron homeostasis. Transcription factor that binds to the PU-box, a purine-rich DNA sequence (5'-GAGGA[AT]-3') that can act as a lymphoid-specific enhancer. Regulates VCAM1 gene expression

• NCBI Gene ID:

  121599

• Swiss Prot:

  Q8N5J4

• Accession Number:

  NP_689536

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SPIC.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Transcription

• Purification:

  Antibody is purified by peptide affinity chromatography method.

• Positive Control:

  Tranfected 293T Cell Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store SPIC antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  29 kDa

• Applications Notes:

  SPIC antibody can be used for detection of SPIC by ELISA at 1:62500. SPIC antibody can be used for detection of SPIC by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  SPIC

• NCBI Official Name:

  Spi-C transcription factor (Spi-1/PU.1 related)

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Carlsson, R., (2006) Biochem. Biophys. Res. Commun. 344 (4), 1155-1160.

• Other Product Names:

  SPIC, MGC40611, SPI-C

• Tested Applications:

  ELISA, WB

• Protein ID:

  22748707

• Physical Properties:

  Liquid