SPIC Antibody

• Background :

  This protein Controls the development of red pulp macrophages required for red blood cells recycling and iron homeostasis. Transcription factor that binds to the PU-box, a purine-rich DNA sequence (5'-GAGGA[AT]-3') that can act as a lymphoid-specific enhancer. Regulates VCAM1 gene expression

• NCBI Gene ID :

  121599

• Swiss Prot :

  Q8N5J4

• Accession Number :

  NP_689536

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SPIC.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Transcription

• Purification :

  Antibody is purified by peptide affinity chromatography method.

• Positive Control :

  Tranfected 293T Cell Lysate

• Concentration :

  Batch dependent

• Buffer :

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store SPIC antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight :

  29 kDa

• Applications Notes :

  SPIC antibody can be used for detection of SPIC by ELISA at 1:62500. SPIC antibody can be used for detection of SPIC by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol :

  SPIC

• NCBI Official Name :

  Spi-C transcription factor (Spi-1/PU.1 related)

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Carlsson, R., (2006) Biochem. Biophys. Res. Commun. 344 (4), 1155-1160.

• Other Product Names :

  SPIC, MGC40611, SPI-C

• Tested Applications :

  ELISA, WB

• Protein ID :

  22748707

• Physical Properties :

  Liquid