SMPD2 Antibody

• Background:

  SMPD2 converts sphingomyelin to ceramide. Hydrolyze 1-acyl-2-lyso-sn-glycero-3-phosphocholine (lyso-PC) and 1-O-alkyl-2-lyso-sn-glycero-3-phosphocholine (lyso-platelet-activating factor) . The physiological substrate seems to be Lyso-PAF.

• NCBI Gene ID:

  6610

• Swiss Prot:

  O60906

• Accession Number:

  NP_003071

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SMPD2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Membrane

• Purification:

  Antibody is purified by protein A chromatography method.

• Positive Control:

  Cat. No. 1211 - HepG2 Cell Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store SMPD2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  48 kDa

• Applications Notes:

  SMPD2 antibody can be used for detection of SMPD2 by ELISA at 1:1562500. SMPD2 antibody can be used for detection of SMPD2 by western blot at 1.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  SMPD2

• NCBI Official Name:

  Sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Kimura, K., (2006) Genome Res. 16 (1), 55-65.

• Other Product Names:

  SMPD2, NSMASE, ISC1, NSMASE1

• Tested Applications:

  ELISA, WB

• Protein ID:

  92859618

• Physical Properties:

  Liquid