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SMPD1 / ASM Antibody

CAT: 0223-16-515Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-16-515Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is a lysosomal acid sphingomyelinase that converts sphingomyelin to ceramide. The encoded protein also has phospholipase C activity. Defects in this gene are a cause of Niemann-Pick disease type A (NPA) and Niemann-Pick disease type B (NPB) . Multiple transcript variants encoding different isoforms have been identified.
NCBI Gene ID
6609
Swiss Prot
P17405
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein of human SMPD1 / ASM
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Apoptosis, Cancer, Cell Cycle, Neuroscience, Signal Transduction
Purification
Affinity purification
Positive Control
THP-1
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 60kDa
Fragment
IgG
Symbol
SMPD1
Positive Control 2
HepG2
Positive Control 3
U-251MG
Positive Control 4
MCF-7
Positive Control 5
Mouse brain
Positive Control 6
Mouse liver
NCBI Official Name
Sphingomyelin phosphodiesterase 1, acid lysosomal
NCBI Organism
Homo sapiens
Other Product Names
SMPD1, ASM, NPD, ASMASE
Tested Applications
WB, IF
Physical Properties
Liquid

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