PPAP2A Antibody

PPAP2A is a member of the phosphatidic acid phosphatase (PAP) family. PAPs convert phosphatidic acid to diacylglycerol, and function in de novo synthesis of glycerolipids as well as in receptor-activated signal transduction mediated by phospholipase D. This protein is an integral membrane glycoprotein, and has been shown to be a surface enzyme that plays an active role in the hydrolysis and uptake of lipids from extracellular space. The expression of PPAP2A is found to be regulated by androgen in a prostatic adenocarcinoma cell line.The protein encoded by this gene is a member of the phosphatidic acid phosphatase (PAP) family. PAPs convert phosphatidic acid to diacylglycerol, and function in de novo synthesis of glycerolipids as well as in receptor-activated signal transduction mediated by phospholipase D. This protein is an integral membrane glycoprotein, and has been shown to be a surface enzyme that plays an active role in the hydrolysis and uptake of lipids from extracellular space. The expression of this gene is found to be regulated by androgen in a prostatic adenocarcinoma cell line. At least two alternatively spliced transcript variants encoding distinct isoforms have been described.

8611

O14494-2

NP_795714

Human, Mouse, Zebrafish

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PPAP2A.

Unconjugated

Primary Antibodies

Cancer

Antibody is purified by protein A chromatography method.

Cat. No. 1205 - Jurkat Cell Lysate

Batch dependent

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

None

Blue Ice

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store PPAP2A antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

31 kDa, 32 kDa

PPAP2A antibody can be used for detection of PPAP2A by ELISA at 1:62500. PPAP2A antibody can be used for detection of PPAP2A by western blot at 2.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

PPAP2A

Phosphatidic acid phosphatase type 2A

Homo sapiens

Tanyi, J.L., Clin. Cancer Res. 9 (10 PT 1), 3534-3545 (2003) .

PPAP2A, LLP1a, LPP1, PAP-2a, PAP2, PAP2a2, PAP2alpha2, PAPalpha1

ELISA, WB

29171738