PPAP2C Antibody

• Background :

  PPAP2C is a member of the phosphatidic acid phosphatase (PAP) family. PAPs convert phosphatidic acid to diacylglycerol, and function in de novo synthesis of glycerolipids as well as in receptor-activated signal transduction mediated by phospholipase D. This protein is similar to phosphatidic acid phosphatase type 2A (PPAP2A) and type 2B (PPAP2B) . All three proteins contain 6 transmembrane regions, and a consensus N-glycosylation site. This protein has been shown to possess membrane associated PAP activity.

• NCBI Gene ID :

  8612

• Swiss Prot :

  O43688

• Accession Number :

  O43688

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  This PPAP2C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 227-254 amino acids from the C-terminal region of human PPAP2C.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Cancer, Signal Transduction

• Purification :

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration :

  Batch dependent

• Homology :

  Predicted species reactivity based on immunogen sequence: Bovine

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  33 kDa

• Fragment :

  Rabbit Ig

• Symbol :

  PPAP2C

• NCBI Official Name :

  Lipid phosphate phosphohydrolase 2

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Long, J.S., Biochem. J. 411 (2), 371-377 (2008)

• Background Reference 02 :

  Morris, K.E., J. Biol. Chem. 281 (14), 9297-9306 (2006)

• Background Reference 03 :

  Nanjundan, M., Am. J. Physiol. Lung Cell Mol. Physiol. 284 (1), L1-L23 (2003)

• Background Reference 04 :

  Zhang, N., Genesis 27 (4), 137-140 (2000)

• Other Product Names :

  Lipid phosphate phosphohydrolase 2, PAP2-gamma, PAP2-G, Phosphatidate phosphohydrolase type 2c, Phosphatidic acid phosphatase 2c, PAP-2c, PAP2c, PPAP2C, LPP2

• Tested Applications :

  WB, Flow

• Physical Properties :

  Liquid