DAZ2 Antibody

CAT: 0223-29-234Size: 100 µLDry Ice: NoHazardous: No
CAT#:0223-29-234Size:100 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
DAZ2 is a member of the DAZ family and is a candidate for the human Y-chromosomal azoospermia factor (AZF) . This RNA-binding protein is important for spermatogenesis.This gene is a member of the DAZ gene family and is a candidate for the human Y-chromosomal azoospermia factor (AZF) . Its expression is restricted to premeiotic germ cells, particularly in spermatogonia. It encodes an RNA-binding protein that is important for spermatogenesis. Four copies of this gene are found on chromosome Y within palindromic duplications; one pair of genes is part of the P2 palindrome and the second pair is part of the P1 palindrome. Each gene contains a 2.4 kb repeat including a 72-bp exon, called the DAZ repeat; the number of DAZ repeats is variable and there are several variations in the sequence of the DAZ repeat. Each copy of the gene also contains a 10.8 kb region that may be amplified; this region includes five exons that encode an RNA recognition motif (RRM) domain. This gene contains one copy of the 10.8 kb repeat. Alternative splicing results in multiple transcript variants encoding different isoforms.
NCBI Gene ID
57055
Swiss Prot
Q2KHN6
Accession Number
NP_001005785
Host
Rabbit
Reactivity
Human
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human DAZ2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. 1224 - Daudi Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store DAZ2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
59 kDa, 65 kDa, 65 kDa, 41 kDa, 65 kDa, 65 kDa, 63 kDa, 50 kDa, 44 kDa
Applications Notes
DAZ2 antibody can be used for detection of DAZ2 by ELISA at 1:62500. DAZ2 antibody can be used for detection of DAZ2 by western blot at 0.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
DAZ2
NCBI Official Name
Deleted in azoospermia 2
NCBI Organism
Homo sapiens
Background Reference 01
Kuo, P.L., (2004) Fertil. Steril. 81 (4), 1034-1040.
Other Product Names
DAZ2, pDP1678
Tested Applications
ELISA, WB, IHC
Protein ID
54292105
Physical Properties
Liquid

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