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TAF6 Antibody

CAT: 0223-28-913Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-28-913Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. TAF6 is one of the smaller subunits of TFIID that binds weakly to TBP but strongly to TAF1, the largest subunit of TFIID. One of the isoforms has been shown to preclude binding of one of the other TFIID subunits, thereby reducing transcription and initiating signals that trigger apoptosis.
NCBI Gene ID
6878
Swiss Prot
P49848
Accession Number
NP_005632
Host
Rabbit
Reactivity
Human, Mouse, Rat, Dog
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TAF6.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription
Purification
Antibody is purified by protein A chromatography method.
Positive Control
Cat. No. 1211 - HepG2 Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store TAF6 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
73 kDa
Applications Notes
TAF6 antibody can be used for detection of TAF6 by ELISA at 1:312500. TAF6 antibody can be used for detection of TAF6 by western blot at 2.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
TAF6
NCBI Official Name
TAF6 RNA polymerase II, TATA box binding protein (TBP) -associated factor, 80kDa
NCBI Organism
Homo sapiens
Background Reference 01
Kimura, K., et al., (2006) Genome Res. 16 (1), 55-65.
Other Product Names
TAF6, TAF2E, TAFII70, TAFII80, TAFII85, MGC:8964, TAFII-70, TAFII-80, TAF (II) 70, TAF (II) 80
Tested Applications
ELISA, WB
Protein ID
5032147
Physical Properties
Liquid